منابع مشابه
Combination Antifungal Therapy for Cryptococcal Meningitis
Jeremy N. Day, M.D., Ph.D., Tran T.H. Chau, M.D., Ph.D., Marcel Wolbers, Ph.D., Pham P. Mai, M.D., Nguyen T. Dung, M.D., Nguyen H. Mai, M.D., Ph.D., Nguyen H. Phu, M.D., Ph.D., Ho D. Nghia, M.D., Ph.D., Nguyen D. Phong, M.D., Ph.D., Cao Q. Thai, M.D., Le H. Thai, M.D., Ly V. Chuong, M.D., Dinh X. Sinh, M.D., Van A. Duong, B.Sc., Thu N. Hoang, M.Sc., Pham T. Diep, B.Sc., James I. Campbell, M.I.B...
متن کاملCombination antifungal therapy for cryptococcal meningitis.
BACKGROUND Combination antifungal therapy (amphotericin B deoxycholate and flucytosine) is the recommended treatment for cryptococcal meningitis but has not been shown to reduce mortality, as compared with amphotericin B alone. We performed a randomized, controlled trial to determine whether combining flucytosine or high-dose fluconazole with high-dose amphotericin B improved survival at 14 and...
متن کاملCryptococcal Meningitis
Virulence probably plays a relatively small role in the outcome of this infection: the crucial factor is the immune status of the host. The most serious infections usually develop, in fact, in patients with defective cell-mediated immunity, for example those with AIDS, organ transplantation, reticuloendothelial malignancy, corticosteroid treatment and sarcoidosis, but not in subjects with neutr...
متن کاملCryptococcal meningitis
© 2004 Blackwell Publishing Ltd the second most common cause of death in HIV infection after tuberculosis (French et al. 2002). Moreover, despite the availability of highly active antiretroviral therapy (HAART), it continues to pose diffi cult management questions in the industrialized world. Questions remain for physicians regarding the optimal combination of antifungal agents, duration of tre...
متن کاملCryptococcal antigen test revisited: significance for cryptococcal meningitis therapy monitoring in a tertiary chinese hospital.
For a total of 29 non-human immunodeficiency virus 1 cryptococcal meningitis cases, titer changes in the latex agglutination test before and after therapy were reviewed along with clinical manifestations, laboratory findings, and therapy regimens. The cryptococcal antigen titer decreased for every case after therapy and was correlated to fungal clearance as defined by fungus smear and/or cultur...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 1996
ISSN: 1058-4838,1537-6591
DOI: 10.1093/clinids/23.2.416-a